A Proposal from Molecular Biology to Clinic

Implication for Gastroinetstinal Cancer

Abstract

Each of esophageal, gastric and colorectal cancers shares characteristic genetic alterations in oncogenes and tumor suppressor genes. We transferred these molecular data to clinical practice and made a new strategy of molecular diagnosis of gastrointestinal cancer as a routine work which has started at Hiroshima City Medical Association Clinical Laboratory since August this year. We believe that this strategy may contribute not only to the development of powerful diagnosis but also to understanding of patient prognosis or therapeutic approaches.