1994 Volume 27 Issue 4 Pages 907-911
A S9-year-old man suffered from carcinoma at the papilla vater which resected by pancreatoduodenectomy. Histopathologically, the tumor showed areas of endocrine cell carcinoma and tubular adenocarcinoma. The specimen was studied by Grimelius' stain, Fontana-Masson's stain and immunohistochemical stain for NSE, tcu7, chromogranin and CEA. The tumor was positive for Grimelius' stain and Leu7 in both areas, and for chromogranin and NSE only in the area of adenocarcinoma, suggesting the same origin of the two components. Furthermore, the neuroendocrine chatracters are exoressed not at the area of endocrine cell carcinoma but at the area of adenocarcinoma.
