Abstract
A study was performed to examine immunohistochemically the T-and B-Iymphocyte, and S-100 protein positive cells populations of regional lymph nodes in patients with gastric cancer. Immunohistochemically, a decrease of T-lymphocytes and dendritic cells, and an increase of B-lymphocytes were observed in metastatic lymph nodes. A decrease of CD4 positive lymphocytes and degenerative change of these cells were also observed. Changes in the level of immunologic parameters in the distribution of immunocytes in regional lymph nodes with or without metastasis may be linked to the progression of cancer.
