Abstract
The present study reports the usefulness of microwave coagulation therapy (MCT) as a new option in the treatment of hepatocellular carcinoma. Twenty-three patients were treated using a microwave monopolar electrode (output 100 watts), from July 1992 to the end of 1994 under open (n=15) or laparoscopic control (n=8). The tumors, superficially located and ranging from 1.3 to 6.5cm in size, were coagulated from the tumor margin toward its center for a total radiation period of 28±9.6 minutes. Postoperative complications were minimal, and the liver chemistries (leaking enzymes, bilirubin, albumin, prothrombin time) returned to the preoperative values within 7 days in most patients. Regular diet was started within a few postoperative days. Follow-up imaging (dynamic CT scan, angiography) suggested complete necrosis. In conclusion, the advantages of MCT include negligible blood loss, technical safety, early recovery, and strong necrotic effect. MCT can be a useful treatment option for hepatocellular carcinoma with severe liver cirrhosis, together with hepatectomy, embolization and ethanol injection.