A Case of Primary Malignant Fibrous Histiocytoma of the Gallbladder

Abstract

A 74-year-old woman was admitted to our hospital because of intermittent epigastric discomfort. Abdominal ultrasound examination and a CT scan showed that the gallbladder with stones, visualized as an irregular wall thickening, continued deirectly with a tumor of the anterior section of the right lobe of the liver. Abdominal angiography revealed an encasement and stenosis in the cystic arteries and a tumor stain in the right lobe of the liver. The patient was diagnosed with the gallbladder cancer with direct invasion to the liver, and underwent extended cholecystectomy. Pathological examination led to a diagnosis of malignant fibrous histiocytoma (MFH). MFH originating from the gallbladder is very rare, and only 7 cases have been reported in Japan so far. This is the eighth case in Japan.