1997 Volume 30 Issue 10 Pages 2004-2008
A 55-year-old man was admitted to our bospital because of anorexia. Tbe laboratory data on admission sbowed marked leukocytosis (21200/mm3). Upper gastrointestinal X ray and endoscopic examination revealed a type 2 gastric cancer at tbe antrum of tbe stomacb. Tbe patient underwent distal gastrectomy witb D2 lympb node dissection on October 30, 1995. Surgical stage grouping was T2, N2, P0, H0, Stage IIIa. Tbe lesion, measuring 110×90mm, was type 5T2 according to macroscopic classification. Patbologic findings were pap, ss, ly3, v3 and n2. From tbe 3rd day after tbe operation to tbe 28tb day, tbe leukocyte count and tbe level of G-CSF in serum fell from 19200/mm3 to 7200/mm3 and 195pg/ml to 60 pg/ml, respectively. Tbe postoperative course was good. Tbe patient was discbarged from our bospital on February 20, 1996. Immunobistocbemical study sbowed positive staining for G-CSF witbin tbe cytoplasm of tbe tumor cells. A diagnosis of a G-CSF-producing gastric carcinoma was made from tbese findings. Tbere bave been only 7 cases of a G-CSF-producing gastric carcinoma in Japan, including ours.
