Abstract
A case of erythropoietin producing hepatocellular carcinoma is presented. A 64-year-old man was referred to the hospital because of a hepatic tumor and erythrocytosis. CT showed a large hepatic tumor in the right lobe and ultrasonography demonstrated tumor thrombus in the inferior vena cava. His serous erythropoietin level was elevated to 1, 510 mU/ml. Trans arterial chemotherapy was not effective and the patient died of the tumor on the 61st hospital day. Necropsy of the hepatic tumor revealed hepatocellular carcinoma of a trabecular type and immunohistochemistory for erythropoietin was strongly positive. Eight cases of hepatocellular carcinoma with erythrocytosis in the Japanese literature are reveiwed.
