Abstract
The clinical feature of hepatic caudate lobe metastasis originating from colorectal carcinoma remains un-clear. We recently experienced two cases of this disease. The first patient is a 69 year-old woman who under-went extended left lobectomy and total caudate lobectomy with partial resection of the inferior vena cava (IVC) for a large tumor that occupied the entire caudate lobe with infiltration to the IVC. Although the post-operative course was uneventful, she had recurrent disease in liver, lung and bone, and is now undergoing chemoradiotherapy 13 months after the operation. The second case is a 56 year-old man, who underwent par-tial resection of the caudate lobe for a metastatic lesion limited to the Spiegel lobe. He is disease free 7months after operation. There have been only 8 reported cases of metastatic caudate lobe cancer from colorectal pri-maries until the present in Japanese literatures. We analyzed the clinical feature of this disease and concluded as follows: 1) Precise diagnosis of the caudate lobe lesion in an early stage is difficult. 2) Median survival time is 25 months, suggesting that aggressive surgical treatment may prolong survival. 3) The majority of postop-erative recurrence sites is the residual liver, which is similar to postoperative findings of liver metastasis in other than tha caudate lobe.