2000 Volume 33 Issue 6 Pages 725-729
A 71-year-old man was admitted to our hospital with nausea and vomiting. Upper gastrointestinal fluoroscopy showed a compression at the duodenal 1st portion without irregularity of the mucosa. Abdominal CT and MRI demonstrated a mass with size of 6 cm adjoining to the duodenum. He was diagnosed as having submucosal tumor of the duodenum and underwent partial resection of the duodenum. Histological findings showed spindle cells with funicular pattern. Immunohistochemically, the tumor showed negative for SMA (smooth muscle actin) and S-100 protein, but positive for c-kit (CD117) and CD34. Then, the tumor was diagnosed as uncommitted type gastrointestinal stromal tumor (GIST). Recently, the concept of the gastrointestinal stromal tumor has become to be popular among surgeons. This case is presented with some notes on the relevant literature.
