Abstract
Background: We assessed the clinical and pathological features of patients with obstructive colorectal carcinoma by age group. Methods: We studied 550 patients with colorectal cancer undergoing colorectal surgery at our hospital, colonic obstruction were seen in 48 (obstructive group); 8 in aged 80 or over, 7 in their 70 s, 15 in their 60s, 18 in aged 40 to 59; 413 of the 550 patients without colonic obstruction (non obstructive group) had cancer that invaded through muscularis propria or further. Results: A significant differences between group were seen in the gender ratio of patients aged 80 or over and in serum CA19-9 in patients aged 40 to 59. In the obstructive group, the rate of emergency surgery, and the rate of curability C were higher than non-obstructive group. Overall survival for the obstructive group was lower with the difference especially great for patients aged 40 to 59. Patients undergoing curability A treatment showed no significant difference in survival from the other groups. Conclusions: Even in obstructive cases, curative cases showed similar survival to non-obstructive cases. It is noteworthy that pre-and/or post-operative multimodal therapy may lead to a better prognosis, especially among younger patients.
