Abstract
A 70-year-old woman underwent partial duodenectomy for duodenal gastrointestinal stromal tumor (GIST). Two solitary metastatic lesions detected in the transverse mesocolon and liver 2.2 years and 6 years after surgery were removed. Since similar pathohistological and immunohistochemical findings were obtained from these 3 tumors, the patient was diagnosed as having c-kit-, CD34-and vimentine-positive GIST. Malignancy tended to be higher in metastatic tumors than in the primary tumor. Duodenal GIST was supplied by the superior mesenteric artery and the left colica. The metastatic lesion in the mesocolon doubled in size in about 85 days. Since the patient survived 7 years after surgery, we recommed active tumor resection when metastatic lesions are detected in regular follow-up at 6-month intervals postoperatively for 10 years or more.
