Preoperative Evaluation of Hepatic Function Reserve by Converted ICGR₁₅ Calculated from ^99mTc-GSA Scintigraphy

Abstract

Purpose: To improve the accuracy of correlation between converted ICGR₁₅ from ^99mTc-GSA Scintigraphy (LHL15, HH15) and ICGR₁₅, we searched for the formula based on the characteristic of LHL15 and HH15. Materials and Methods: Preoperative hepatic function reserve was evaluated by converted ICGR₁₅, calculated with a formula acquired from the correlation between HH15 and ICGR₁₅, or the correlation between LHL 15 and ICGR₁₅. Subjects were 144 patients undergoing hepatectomy after ^99mTc-GSA scintigraphy and indocyanine green retention test from June 1995 to September 2002. Results: Based on the fact that LHL15 is correlated with ICGR₁₅ in cases with better hepatic function reserve, and HH15 is correlated with ICGR₁₅ in cases with poorer hepatic function reserve. Two separate formulas were found in Liver Damage A and Liver Damage B to improve the correlation coefficient. ICGR₁₅=114-108× LHL15 was found in cases with Liver Damage A, and ICGR₁₅=-41+103× HH15 in cases with Liver Damage B. Conclusion: ICGR₁₅ converted from these formulas related better to ICGR₁₅ than that from the formula acquired from all cases.