A Case Report of Colon Cancer with Multiple Liver Metastases Successfully Treated by Hepatic Arterial Infusion Chemotherapy of 5-FU, l-LV, CPT-11 and Hepatic Resection

Abstract

A 54-year-old Japanese man with cecal cancer and multiple liver metastases (CEA: 95.0 ng/ml) who under-went ileoceal resection followed by implantation of hepatic arterial infusion was treated postoperatively with 5-fluorouracil, leucovorin, and irinotecan hydrochloride. Since metastatic liver lesions all shrunk markedly after 6 Kur of chemotherapy (CEA: 10.6 ng/ml), and no other metastatic lesion was seen, we resected the liver tumors. He remained alive for 14 months after the first operation. This case is rare in having multiple me-tastasis of colorectal cancer controlled by radical surgery, and chemotherapy with 5-FU, l-LV, and CPT-11.