Abstract
We report a case of gastrointestinal stromal tumor (GIST) of the duodenum with liver metastasis. A 50-yearold woman admitted for appetite loss and abdominal pain was found in upper gastrointestinal endoscopy to have a tumor with ulceration at the 2nd portion of duodenum. Abdominal computed tomography showed a mass 10cm in diameter involving the duodenum and a low-density mass in the liver, necessitating pyloruspreserving pancreatoduodenectomy and hepatectomy. Histopathologically, the tumor arose from the proper muscle layer of the duodenum, and was positive for c-kit and negative for CD34, S100 protein, and SMA on immunostaining. The tumor was diagnosed as combined malignant GIST.
