Abstract
A 67-year-old man presenting with erythroderma-associated hepatocellular carcinoma had previously developed pruritic erythrodermic lesions. Examinations showed hepatocellular carcinoma in segment 7, necessitating right hepatic lobectomy. After surgery, the man's erythroderma completely disappeared. In Japan, 63 cases of erythroderma-associated internal solid cancer have been reported. Ours is the second case of erythroderma-associated liver cancer. We discuss the relationship between erythroderma and solid cancer based on a review of the literature.