Abstract
We report a case of squamous cell carcinoma that developed in the ascending colon. The case was a 51-year-old man with lower abdominal pain as the chief complaint. Cancer of the ascending colon accompanied by mul-tiple metastases in the liver was diagnosed, for which right hemicolectomy was performed. In histopathologi-cal examination of the total segmentation of surgical specimen, adenomatous component was detected but adenocarcinomatous component was not, and keratosis was observed, from which moderately differentiated squamous cell carcinoma was diagnosed. The patient was discharged on the day 27 after operation, but died of cancerous cachexia on day 65. As for the development of this disease, carcinogenesis from adenoma was indi-cated because of the involvement of an adenoma element. Because at the time of diagnosis many patients with this disease had already developed remote metastasis, the prognosis is not favorable. Advances in multidisci-plinary treatments are expected to improve the results of treatment.