Abstract
A 64-year-old woman was admitted to our hospital for further examination, it was known that she had a gallbladder tumor before admission. Abdominal ultrasonography showed an iso-echoic mass lesion about 1 cm in diameter in the neck of the gallbladder. T1-weighted MRI showed an irregular iso-intense mass. Laparoscopic cholecystectomy and frozen section examination were performed. Gallbladder carcinoma was suspected based on the frozen-section findings, but invasion of the muscularis propria was unclear. Macroscopic examination of the resected specimen revealed a mulberry like mass measuring 12×8mm-size. Microscopic examination of the tumor revealed tumor cells in a trabecular pattern and containing round, hyperchromatic nuclei. The tumor cells were positive for Grimelius staining and immunohistologic chromogranin A staining. The patient is doing well, with no any signs of recurrence, 12 months after the operation.