Elevation of Plasma Sialic Acid and Serum Haptoglobin in Experimental Animals in Relation to Triglyceridemia induced by Cobalt Chloride Administration

Abstract

An elevated plasma sialic acid concentration was found in rabbits and rats associated with triglyceridemia induced by cobalt chloride administration. Acrylamide gel electrophoresis of the serum from rabbits treated with cobalt chloride showed augmentation of the band corresponding to haptoglobin.
Serum haptoglobin levels were determined with cellulose acetate electrophoresis, and were found to increase in cobalt treated rabbits and rats.