Abstract
This paper discusses 60 cases of untreated oropharyngeal squamous cell carcinoma and 2 cases of undifferentiated carcinoma of the tonsilar region and tongue base, in the period from 1993 until 2003.
As a treatment policy, operation was performed in principle, and in the cases of pN2-3, postoperative irradiation of 44-50Gy was given to the whole neck.
As a result, 41 cases of cancer of the tonsilar region, even advanced cases, could be well controlled, and the five-year cumulative survival rate was 71.2%.
On the other hand, cancers of the tongue base were difficult to control and the five-year cumulative survival rate was 21.5%.
Therefore, the treatment strategy for tongue base must be checked. CR was achieved with a case of T4N2c by an intra-arterial infusion of CDDP three times in combination with radiation of 70Gy. In this case the patient was able to return to work after treatment.
It is thought that concurrent intra-arterial infusion and radiation is a useful method for tongue base carcinoma.
