New superselective intra-arterial infusion for lower gingival cancer

—Method of two simultaneous catheterization combined with arterial redistribution from superficial temporal artery—

Abstract

We devised a new method of superselective intra-arterial infusion from the superficial temporal artery for lower gingival cancer. Arterial redistribution by embolization with micro coils was performed in the periphery of the tumor, then two micro catheters were placed superselectively in both the facial and intermaxillary artery.
We applied this technique to a case of lower gingival cancer (T3N0M0). Chemotherapy using intra-arterial infusion (5-FU 100-50mg/m²/day, TXT 15mg/m²/week, CDGP 20mg/m²/week) combined with radiation therapy (total 40Gy) was performed for 4 weeks. The clinical effect was complete response (CR). No operation was performed.
This technique is highly effective for local control with minimal adverse events by using anti-cancer drugs for lower gingival cancer, and showed the possibility of organ preservation.