2010 Volume 36 Issue 1 Pages 43-47
Epithelial dysplasia and local recurrence at the resected margins in 43 patients who underwent primary curative surgery for early stage oral squamous cell carcinoma (T1 or T2) without any preoperative treatment were discussed, respectively. Of the 43 patients, 19 had epithelial metaplasia at the resected margins, including seven in whom recurrence developed. Among the 24 patients with no epithelial dysplasia, one had recurrence. These results suggested that the presence of epithelial dysplasia the resection margins is closely related to recurrence. Among the 19 patients with epithelial dysplasia, there was no significant difference in the histologic malignancy grade of their primary tumors according to Anneroth's classification between patients with recurrence and those without recurrence. Patients with residual dysplasia who had recurrence of tongue cancer were analyzed according to the classification of squamous intraepithelial neoplasia (SIN) proposed by the “Guidelines for Tongue Cancer” Working Group, affiliated with the Japan Society for Oral Tumors. All of these patients met the criteria for SIN. This finding suggested that the classification of SIN is useful for the evaluation of epithelial dysplasia at the resection margins in patients with oral squamous cell cancer.
