A clinical analysis of hypopharyngeal carcinoma: single-institution outcomes

Abstract

We report the treatment outcomes of 195 patients with hypopharyngeal carcinoma treated at our institute during the nine-year period between 2001 and 2009. The five-year overall survival rate and cause-specific survival rate of all patients except for M1 cases were 47.7% and 56.8%. The five-year cause-specific survival rates of patients with Stage I, II, III, VIa and VIb were 80.2%, 86.9%, 66.8%, 45.5 and 0.0%, respectively.
We consider that TPLE and CCRT are standard treatments. We select CCRT for patients of CR or PR after induction chemotherapy. The five-year cause-specific survival rate of the ICT good response (CCRT) group, good response (TPLE) group, poor response (CCRT) group, and poor response (TPLE) group were 68.7%, 65.6%, 53.6%, and 32.9%, respectively. Patients of the good response (CCRT) group had a good prognosis, but patients of the poor response (TPLE) group had a poor prognosis.