2014 Volume 40 Issue 4 Pages 422-425
We report a case of combined small cell carcinoma and adenocarcinoma (CSCCA) in the ethmoid sinus. A 53-year-old man was seen for left nasal bleeding and left neck induration. Computed tomography showed swelling of the left ethmoid mucosa and neck lymph nodes. Nasal tumor biopsy yielded a diagnosis of CSCCA. He was treated with irradiation (total dose 74Gy/37fr), and neck dissection and paranasal surgery by the external incision method. No recurrence has been seen in the 5 years since initial treatment. The reason for the long-term survival is suggested to be that the Ki–67 labeling index showed a lower grade of tumor cells.