2024 Volume 50 Issue 1 Pages 6-12
We examined retrospectively the effect of postoperative radiotherapy for salivary gland cancer performed at our hospital. There were 104 eligible patients, of whom 75 (72%) received postoperative radiotherapy. For all patients, the 3-year locoregional control (LRC) rate was 90.3% (95% CI 82.8-97.9%) in the group with postoperative radiotherapy and 71.2% (95% CI 52.9-89.5%) in the group without postoperative radiotherapy, and was thus significantly better in the group with postoperative radiotherapy (p=0.02). For the patients with parotid gland cancers, the 3-year local control (LC) rate was 93.0% (95% CI 86.4-99.7%) in the group with postoperative radiotherapy and 66.6% (95% CI 42.4-90.9%) in the group without postoperative radiotherapy (p<0.01). Multivariate analysis showed that postoperative radiotherapy was the only independent risk factor in LRC for all patients, and in the analysis of parotid gland cancers, high grade malignancy and postoperative radiotherapy were independent risk factors in LC.