The Japanese Journal for the Histrory of Pharmacy
Online ISSN : 2435-7529
Print ISSN : 0285-2314
ISSN-L : 0285-2314
Transitions of psychotropic drugs in the Japanese Pharmacopoeia (JP) (Part 14). Transitions in the standards and test methods of Valerian root in the Deutsches Arzneibuch (DAB) and comparison between the USP, BP, EP and JP, and Oleum Valerianae (Japan Kesso oil) listed in DAB6 (1926)
Kiyohisa Yanagisawa
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2014 Volume 49 Issue 2 Pages 176-189

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Abstract

Valerian has been used as a name for Japanese Valerian and European Valerian root. Valerian in the German market today was originally called Baldrian. Transitions in the standards and the test methods of Valerian root listed in the DAB were studied this time. Moreover, we compared these standards and test methods with those in the USP, BP, EP and JP. We also considered the pharmacology evaluation in Germany. At the time, the standards and test methods had content in accordance with the EP from DAB9 (1986) of the West Germany publication. It also agreed with the EP and BP of the same period. To date in the DAB, botanical features have been mainly derived from the discriminating characteristics of the Valerian root. In DAB9 (1986), standards and test methods were added to the content, enhancing it and making it more stringent. This is thought to have happened as a result of a new, academic finding showing an improvement in the pharmacology level. Valerian root has been listed continuously in the DAB. These listings suggest that Valerian root has continually been evaluated as a sedative. We think that the listing was connected with a relisting in the BP as a result of scientific communications between Britain and Germany, EC member nations, such as through EP publications. On the other hand, the oil made with Japanese Valerian was listed in a radical field in DAB6 (1926) in the past. This is a valuable result, proving that it was used and evaluated as an important herbal medicine from Japan and foreign countries at that time. The Japanese Valerian referred to is not grown in Japan today. Moreover, it is not possible that cultivation will be restarted through good quality revaluation. However, this fact introduces a valuable piece of history supporting the survival of Japanese Valerian and European Valerian root as a sedative in the future. PMID: 25799839 [Indexed for MEDLINE]

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© 2014 The Japanese Society for the History of Pharmacy
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