Abstract
No functional testing methods to observe the recovery process of patients undergoing treatment with an ileus tube have yet been proposed. In this study, we developed a system that measures small intestine motility as changes in balloon pressure attached to an ileus tube during treatment, using a pressure sensor. As a preliminary technical evaluation of the system, we conducted measurements on five healthy volunteers: three received metoclopramide to promote motility, and two received butylscopolamine bromide to suppress it. We assessed whether the system, along with its signal analysis methods—specifically, time-domain and time–frequency analysis using wavelet transform—could quantitatively detect drug induced changes in motility. After metoclopramide administration, pressure fluctuations increased by approximately 0.2–0.4 kPa in the 1–2 cycles/min range, along with increased spectral power and activity. Conversely, approximately 27 seconds after butylscopolamine bromide administration, a pressure drop of 0.5–1.0 kPa and decreased activity in the 1–2 and 6–11 cycles/min ranges were observed. These results suggest that the system, combined with appropriate signal analysis methods, is technically capable of quantifying motility changes and may serve as a useful tool for clinical monitoring.
https://ror.org/03hv1ad10 
