Abstract
A 16-month-old Holstein heifer was presented with the chief complaint of maldevelopment. The heifer was 110 cm in height and severely emaciated. Laboratory findings including non-regenerative anemia, azotemia, elevated serum creatinine, hyperphosphatemia, hypocalcemia, low urine specific gravity and proteinuria strongly suggested chronic renal failure. Although the heifer was treated by infusion, edema developed on the lower jaw and the brisket on Day 15. After its death on Day 16, necropsy revealed chronic interstitial nephritis with glomerular lesions, but the cause was undetermined.
