Abstract
Both dental caries and periodontal disease are caused by hyperpathogenicity of biofilms. Biofilm hyperpathogenicity is referred to as dysbiosis, a phenomenon in which environmental changes such as nutrition, temperature, pH, and anaerobic conditions surrounding the biofilm activate the bad bacteria （cariogenic or periodontopathic bacteria） to multiply and increase the pathogenicity of the biofilm. Dysbiosis causes the biofilm to shift from a stable state （symbiosis） to a highly pathogenic state. As a result, The equilibrium between the aggressive forces of the biofilm and the defensive forces of the teeth and periodontal tissues is upset, and dental caries and periodontal disease develop.
Caries dysbiosis is initiated by the feeding of fermentable sugars （sugar, glucose, fructose, lactose, and cooked starch） to multiple acid-producing bacteria. Periodontal dysbiosis begins as a nutritional symbiosis between bacteria that starts in an old biofilm, and then becomes full-blown when the biofilm is fed proteins and iron by bleeding from periodontal pockets. The prevention and treatment of dental caries and periodontal disease is the elimination of dysbiosis.
