Abstract
We experienced a case of anesthetic management for 45-year-old male patient with a family history of malignant hyperthermia in tongue cancer resection. Premedication was performed atropine and midazolam. General anesthesia was induced with propofol 140mg and vecronium 8 mg with fentanyl 50μg. After nasotracheal intubation, anesthesia was maintained with nitrous oxide, oxide, and propofol (3-8 mg/kg/hr), intermittent fentanyl and vecuronium. Operation time was 2 hours 39 minutes and anesthesia time was 4 hours 33 minutes. Bladder temperature, breast core temperature, elbow core temperature, and thumb skin temperature were monitored during anesthesia. The intraoperative course was uneventful. The patient's bladder temperature increased 37.9°C in the seven hours after operation. He was treated with cooling and NSAID suppositories. His temperature slowly decreased. Intraoperative and postoperative blood myoglobin had increased to 94 and 111ng/ml, and postoperative CK had increased to 253 IU/l.
