A case of post-extraction hemorrhage in a patient with a chronic disseminated intravascular coagulation (DIC) complicated by dissecting aortic aneurysm

Abstract

A case of post-extraction hemorrhage with chronic disseminated intravascular coagulation (DIC) due to dissecting aortic aneurysm is report-ed. The patient, a 75-year-old male was referred to our hospital with his persistent hemorrhage after extraction of 432_??_13 and the alveoplasty. He had received surgical replacement of artificial vessel for the aneurysm 5years ago. Hematological examination suggested his coagulation disorder and then we preformed local hemostasis at upper jaw. Investigation of blood coagulation factor and chest MRI diagnosed him as chronic DIC resulted from the aneurysm of inferior aorta.
The patient after evidenced gingival bleeding, and camostat mesilate was administered orally in a daily dose of 600mg.
When we take an invasive treatment to a patient with chronic DIC who has systemic background such as an aortic aneurysm, the post operative hemorrhage should be taken care.
It is suggested that oral administration of camostat mesilate is effective for the postsurgical bleeding because of chronic DIC.