Abstract
Myelodysplastic syndrome (MDS) is a postnatal blood formation disorder with preleukaemia and obstinate anemia. Surgical procedures must take into account bleeding tendency in addition to the fact that the host is immunologically compromised (prone for infection). Two cases of myelodysplastic syndrome where the general physical condition was aggravated following oral surgery are herein reported.
Patients were hospitalized and treated by a hematologist. Post-surgical evaluation revealed that the surgical site was inflamed with decrease in platelet and neutrophil counts, increase in CRP, as well as having tolerance to antibiotics.
Patients were administered several kinds of antibiotics, platelets and granulocyte colony stimulating factors which resulted in improvement and alleviation of their symptoms.
In MDS patients, when the surgical sites are infected in spite of efforts toward prevention, it is possible symptoms may deteriorate rapidly. Therefore, it is of importance that the patients are to be treated by oral surgeons and hematologists.
