Abstract
Thalassemia is a congenital hemoglobin anomaly that presents as a hemolytic anemia. The incidence in Japan is rare. We selected to perform dental treatments under general anesthesia for behavioral control in a Down syndrome patient with thalassemia. The patient is 20-years-old, male, 155.0cm in height and weighing 72.5kg. He was diagnosed with Down syndrome and thalassemia immediately after birth. We confirmed hypochromic microspherocytosis during the preoperative evaluation and analyses and a decrease in the reserve force for the hypoxic state was predicted. After nasal intubation, general anesthesia was maintained with N2O+oxygen+sevoflurane. There were no complications encountered with anesthesia during and following the dental procedure. Careful preoperative evaluation and analyses, correct diagnosis and precautious anesthetic manipulations are required to administer general anesthesia in patients with Thalassemia.
