Abstract
This paper report our recent experience of four patients who developed drug-induced allergic reactions.
Cose No 1 had a history of allergy to drugs and various foods. This patient underwent extraction of the left upper first and third molar teeth after preoperative allergy tests and prophylactic measures including steroid therapy, and exhibited only slight allergic symptoms in response to lidocaine used as a local anesthetic.
Case No 2 developed serious anaphylactic shock several minutes after an oral dose of talampicillin following alveoloplasty. The patient showed a temporary fall of bloodpressure, causing difficulties with treatment.
Case No 3 and 4 developed allergic symptoms in response to latamoxefsodium administered intravenously for resolution of acute inflammation. Case 3 had no history of drug hypersensitivity. Threee Case excluding Case 2 underwent preoperative intracutaneous tests.
Case 1 had a strongly positive reaction, showing facial flushing, even though the test drug was diluted.
Case 3 and 4 showed allergic symptoms even though their preoperative tests had been negative.
Our experiences indicate that intracutaneous tests are not wholly reliable, and that caution should be exercised when administering drugs during dental treatment.
