Abstract
Steroid hormones have immunosuppressive and anti-inflammatory properties. Therefore, the drugs administered in the treatment of many diseases. Recently, we had the experience of treating the case of a 37 year old female patient with lip carcinoma. This patient had been prescribed steroid hormone for treatment of her ulcerative colitis extend over a long period time. She was admitted to our clinic for treatment of a lower lip ulcer. The clinical findings suggested that malignant neoplasmus, however some consideration was given to the possibility that the lip ulcer was complication of the ulcerative colitis and that the healing of the wound was affected negatively by the immunosuppress property of the steroid hormone. Therefore, antiulcerative ointment was applied locally. But the ulcerative legion began to increase in size so a biopsy was performed quickly. Histopathological diagnosis was squamous cell carcinoma, so after the radiotherapy tumor excision, bilateral supraomohyoid neck dissection and immediate reconstruction using forearm skin flap was performed. Postoperative course was uneventful, although the patient noticed some stiffness in the left upper neck region. Through the use of a CT examination, a metastatic legion in a deep part of the cervical lymph-node was suspected. A radical neck dissection was performed in the usual manner. One month after the operation, multiple metastasis occurred in the cervical and temporal regions, the lung and the acetabulum.
This case suggests there is the possibility that increasing incidence of metastasis occures in immunosuppressed patients.
