Experiences of tooth extraction in patients with platelet-transfusion refractorystatus

Abstract

We have reported that platelet-transfusion have no effect for two cases of toothextraction in patients with aplastic anemia and also idiopathic thrombocytopenic purpura (ITP).
In case I, a reaction was not admitted to the platelet transfusion. Because of transfusing many time. the human leukocyte antigen (HLA) antibody had made. But, hemostasis was possible with the HLA-PC transfusion and also granulocyte colony stimulating factor (G-CSF) and erythropoietin (EPO). In case 2, althouth we use high doses of γ-globulin and ulatelet transfusion, the rise of blood platelet was not admitted. Therefore, hemostasis was possible with steroids and platelet transfusion and also local hemostasis.