Particle Motion Analysis is Solid Dosage Equipment by DEM Simulation and Application to Equipment Development

Abstract

The high speed mixing granulator, the fluidized bed granulator/dryer, the tumbling fluidized bed to which a rotor is added, and the rotating drum type tablet coating equipment are widely used for solid dosage manufacture. Rationalization of operating conditions according to the physical properties of various materials has been a big subject. Therefore, for these equipments, the phenomenon inside these equipment are analyzed especially on particle motion by DEM analysis. Some example data examined about the features of these equipments performance are introduced, and the application to future development of equipments is explored.