Abstract
A total of 155 sporotrichosis cases examined in Nagasaki prefecture, including 138 cases which had been previously reported and 16 examined from 2002 to 2007, were surveyed and compared. No significant differences were found between 143 cases from 1951 to 2001 and 12 of these from 2002 to 2007 in sex or the affected regions of the body. Males and females were equally affected. The lesions were frequently seen on the face(28.2%, 25.0%)and upper limbs(62.1%, 66.7%). Fixed type(62.1%)was much more frequent than the lymphocutaneous type(37.9%)from 1951 to 2001, but in recent year there was an equal number of two types. The rate of patients over 50 years of age increased from 72.1% to 91.7%, and of note was that there were no patients under 10 years and only 2 was noted over 90 examined after 2002. A remarkable increase in the number of cases in Shimabara area(26.8% → 33.3%). Prior to 1994, potassium hydroxide(KI)was used as therapy in most cases(99.1%), but after 1995, itraconazole was used in over 50% of cases and those treated with terbinafine also increased. KI was used in about 20% of case after 1995 decreasing from then to 2000(8.3%), recently, its use has again increased(25.0%). The period of treatment until cure was achieved for itraconazole was 17.0 weeks and for KI was 10.9 weeks.
