Statistical Evaluation of the Cases with Deep Mycosis in Japan

Abstract

The results of our statistical evaluation of 1896 cases with deep mycosis in Japan for 5 years since 1970 up to 1974 based on the Annual of the Pathological Autopsy Cases in Japan and of 201 cases based on the nationwide statistics for 5 years and 7 months since 1971 up until July 1976 were comparatively studied with the previous results elsewhere reported. The former group comprised 654 cases with candidiasis, 513 with aspergillosis, 232 cases with cryptococcosis, and 57 cases with mucormycosis in the order of frequency. Of the total, 1804 (95.1%) were the secondary cases. The fundamental diseases were leukemia, solid tumors, hematological diseases, malignant lymphoma, and hepatic diseases. The pathological changes were noted frequently in lungs and bronchus in the cases with aspergillosis, digestive tracts in the cases with candidiasis, lungs, brain, and kidneys in the cases with cryptococcosis, and lungs, kidneys and hearts in the cases with mucormycosis. Of the 201 cases of the latter group, the order of the frequency was similar to that of the former group, in which pulmonary mycosis shared about half. As the results of advanced therapeutic treatments, a type of mycosis with substitution by artificial valve for the 23 cases with renaltransplantation could also be experienced in 12 cases. This information will be of some help for evaluation of the present status of the cases with mycosis in Japan.