Fungicidal Activity of Povidone-Iodine

Abstract

Fungicidal activity of Povidone-Iodine (PVP-I) against 7 species of Candida, Torulopsis glabrata, Cryptococcus neoformans and 10 strains of fresh isolates of C. albicans was examined. A similar fungicidal activity of PVP-I against all these yeast strains was demonstrated. Although the fungicidal effect of PVP-I was significantly decreased in the presence of serum, it was found that the fungicidal activity become apparent within 1 to 3 minutes under the effective concentration of PVP-I (3mg/ml/10⁸ yeasts in 10% serum). Further, rapid and potent disinfecting effects of PVP-I were manifested against animal skin and stainless steel tools artificially contaminated with C. albicans.