Abstract
A-62-year old female, under treatment with systemic corticosteroids, developed widespread ulcerative lesions on her left leg. Histological examination revealed granulomatous inflammatory changes containing few microorganisms, typical of Prototheca species. Culture of the specimen using several different media, however, yielded no microorganisms. This is the second case of protothecosis reported in Japan. Possible reasons for the failure to isolate pathogens were discussed.
