Abstract
The efficacy and safety of a weekly oral dose of 100mg of fluconazole in the treatment of tinea unguium were evaluated in 18 patients, 4 with fingernail tinea and 14 with toenail tinea. After a 24 week follow-up, the clinical effects were excellent in 8 (44.4%), good in 8 (44.4%), fair in 1 (5.6%) and poor in 1 (5.6%). No side effects or abnormal laboratory findings were observed. Both the efficacy rate and the utility rate were 88.9% (16/18). This study suggests that a weekly dose of fluconazole is useful in the treatment of tinea unguium.