Is Skin Irritation of Topical Antifungal Agents Improved?

Abstract

Commercially available topical antifungal agents pose no serious safety problems, but no agent is free from side effects in all patients. Allergic contact dermatitis caused by an antifungal agent and/or vehicle has been reported and we have experienced some cases of this. However, it seems to us that primary skin irritation is caused mainly by the vehicle. Types of skin irritation are immediate, primary and dry skin irritation. In the new commercially available topical antifungal agents, primary skin irritation has been almost improved.