Abstract
The clinical and antifungal effects of topical terbinafine treatment were studied in 24 cases with tinea pedis. The antifungal effects were evaluated by the KOH direct microscopic examination, slant culture, and foot-press culture which showed the dissemination of dermatophytes from the feet. Before the treatment dermatophytes were isolated from 17 cases (70.8%) by the foot-press culture, and from 18 cases (75.0%) by the slant culture. The negative rate of the KOH direct microscopic examination and the rate of clinical improvement were low in the first and second week after the treatment, but the rates of the foot-press culture were very high during this period.
Therefore, it can be concluded that the treatment with topical terbinafine cream reduces relative quickly the dissemination of dermatophytes from the feet of tinea pedis patients.