Abstract
A 46-year-old Japanese man visited our clinic because of a persistent subcutaneous nodule of the right foot. The lesion was 2×1.5cm in size and had no sinus. Multiple hard black granules Ca. 1mm in size were found in the fibrous hard dermal tissue at the time of biopsy. The histological examination revealed inflammatory granulomatous reaction in both the dermis and subcutaneous fat tissue. Hyphal and chlamydospore-like elements were observed in biopsied specimens stained with PAS and GMS. A black colony was developed on Sabouraud's dextrose agar from these black granules and identified as Madurella grisea. From these findings, the lesion was diagnosed as mycetoma. The infection route is unknown.
Total excision was performed. To our knowledge, this is the first case of mycetoma pedis caused by Madurella grisea in Japan.
