Abstract
A case of a 9-year-old female with chronic mucocutaneous candidiasis (CMCC) is described. She had onychomycosis and stomatitis at the age of 5, and developed deep dermal nodules on the scalp 1 year ago. Histological finding in PAS stain revealed fungal elements in the upper dermis. Candida albicans was cultured from the lesions. Lymphocytic transformation test to Candida showed hyporeponsiveness, but delayed dermal reaction (delayed-type hypersensitivity) to Candida was normal. She had no other disorder such as endocrine failure. Treatment with fluconazole was successful. Her mother was CMCC with hypothyroidism and her brother had candidial stomatitis, so this patient was diagnosed with familial CMCC.
