Abstract
Non-invasive pulmonary aspergillosis is generally accepted as a non-active and static condition because the passage is long and the subjective symptoms are mild in the early stage. New concepts of “semi-invasive pulmonary aspergillosis” and “chronic necrotizing pulmonary aspergillosis” have recently been acquiesced citation. However, these new categories have caught confusion of the terminology and improper clinical application because of their incomplete definition. The process of typical pulmonary aspergilloma has still not examined. By X-ray image, we analyzed the progression of non-invasive pulmonary aspergillosis in 41 patients. These were able to recognize all passages until full development of the disease from prior to the individual's recovery from the preceding lung disease. We found that non-invasive pulmonary aspergillosis does not progress in only one direction, but repeatedly become worse and then improves. This process ultimately leads to a largely destroyed pulmonary parenchyma and a fatal outcome. Non-invasive pulmonary aspergillosis has a dynamic course, and we therefor do not believe that a distinction of “semi-invasive pulmonary aspergillosis” is needed. Once fungus ball formation is confirmed, the anti-fungal drugs available at present are not effective for treatment. Early diagnosis and early chemotherapy is critical.
