Visualization of Water Dynamics on the Rat Cerebral Surface Using Direct Infusion of ¹⁷O-Labeled Water into the Subarachnoid Space and Proton MRI [Presidential Award Proceedings]

Abstract

　We investigated the feasibility of visualizing water dynamics on the rat cerebral surface by direct injection of ¹⁷O-labeled water into the subarachnoid space of the cerebral cortex. We observed its dynamics on the rat cerebral surface, providing potential insights into the glymphatic hypothesis.