Echocardiographic assessment of the relationship between left ventricular geometry and dyssynchrony

Abstract

Purpose: The purpose of this study is to show the relationship between LV geometry (spherical or ellipsoid) and LV dyssynchrony. Subjects and Methods: The study population consisted of 25 patients (5 females and 20 males, ages 64±14 years) with severe LV systolic dysfunction (LV ejection fraction⟨35%). LV geometry was assessed with the ratio of LV longitudinal dimension / radial dimension (sphericity index: SI) in the 2D echo. LV dyssynchrony was assessed with Ts-SD, determined with 2D tissue Doppler, and systolic dyssynchrony index (SDI), determined with 3D full volume. We examined the relation between SI and the degree of dyssynchrony, and the effect of medical treatment on the relation. Results and Discussion: SI correlated with SDI (r=-0.44, p⟨ 0.05), while there was no correlation between SI and Ts-SD (r=-0.22). LV geometry was more ellipsoid and LV dyssynchrony was smaller in those receiving beta-blockers, angiotensin-converting enzyme inhibitors / angiotensin receptor blockers, and statins than in those not receiving these. Conclusion: There was a correlation between LV geometry and LV dyssynchrony. LV geometrical change from ellipse to sphere may facilitate LV dyssynchrony in patients with severe LV systolic dysfunction.