2019 Volume 8 Issue 2 Pages 163-170
Introduction: Some over-the-counter (OTC) drugs for peptic ulcers contain sodium bicarbonate in order to neutralize gastric acid. Therefore, the ingestion of sodium bicarbonate increases the sodium intake, which is affected by salt ingestion, and these drugs must be carefully consumed. The purpose of this study was to investigate the salt-converted volume of sodium bicarbonate contained in OTC drugs for peptic ulcers and the status of information provision to customers by registered pharmacy sellers.
Methods: The salt-converted volume of sodium bicarbonate was investigated at the Self-Medication Database Center. A questionnaire survey involving registered pharmacy sellers was conducted to examine consciousness regarding the association between sodium bicarbonate contained in drugs for peptic ulcers and chronic kidney disease (CKD), as well as information provision to customers.
Results: The sodium bicarbonate content of an OTC drug for peptic ulcers accounted for 26 - 53% of the maximum daily intake, regarding the daily salt intake limit as 3 - 6 g. Furthermore, 79.2% of the registered pharmacy sellers had confirmed the drug history through “patient interviews” when selling these drugs, whereas 81.8% had never provided information or consultation services to dialysis/CKD patients. Furthermore, 20.8% had paid attention to the volume of sodium bicarbonate contained in drugs for peptic ulcers, and 15.6% recognized that 1 g of sodium bicarbonate was converted to 0.7 g of salt.
Discussion: This study demonstrated that the level of consciousness regarding the salt-converted volume of sodium bicarbonate contained in drugs for peptic ulcers was low despite “patient interviews” by the registered pharmacy sellers, and that neither information nor consultation services were frequently provided to CKD patients. Therefore, it may be necessary to educate registered pharmacy sellers through lecture meetings, pharmacist association training, and announcement of information from kidney-disease-associated societies.