Two Cases of Cheilitis Granulomatosa Successfully Treated by Removal of Infectious Foci of Apical Periodontitis

Abstract

We report two cases of cheilitis granulomatosa (CG) successfully treated by removal of infectious foci of apical periodontitis. Case 1: The patient was a 70-year-old man who complained of swelling of the lower lip one month earlier. Biopsy specimens showed granulomatous change including multinucleic giant (Langhans giant cell) cells, and diagnosed as CG. Case 2: The patient was a 41-year-old woman who complained of swelling of the lower lip two months prior to her first visit. Biopsy specimens showed granuloma with epithelioid cells, and diagnosed as CG. Panoramic X-rays of these two patients revealed a periapical radiolucency of the left mandibular first molar. Both of these cases were underwent extraction of the left mandibular first molar. Swelling of the lower lip was gradually regressed within three months after the tooth extractions. Dental focal infection was thus considered as a cause of CG in these patients.